CUSAT

Dr. Sreeja Narayanan
Wellcome Trust/DBT Early Career Fellow

Department of Biotechnology

Email: narayanan.sreeja@gmail.com
Phone:

Dr. Sreeja Narayanan received her PhD from the Amrita Centre for Nanosciences and Molecular Medicine in Nanobiotechnology for her work on the design and application of polymeric core/shell nanomedicine for sequential drug delivery in breast cancer therapy. She did her postdoctoral training from the Department of Biotechnology, Cochin University of Science and Technology. She obtained her Masters in Science (Biotechnology) for the Mahatma Gandhi University and Masters in Technology (Nanomedical Science) from Amrita Vishwavidyapeetham. Presently, she is the Wellcome Trust/DBT Fellow at the Department of Biotechnology.

Research Interest
Triple-negative breast cancer (TNBC) is a clinically heterogeneous and molecularly diverse subset of breast cancer with high levels of mutations leading to large numbers of immunogenic neo-antigens that helps the tumor to escape the innate immunity surveillance. My interest is in developing biomimetic constructs for specific stimulation of the immuno-microenvironment in TNBC so as to aid improved therapy.

Awards and Honors
â€¢ Vice-Chancellorâ€™s Letter of Appreciation for research accomplishments at CUSAT, 2020
â€¢ DBT-Wellcome Trust Early Career Award, 2020, Indo-UK Alliance, Govt. of India
â€¢ UGC-DS Kothari Postdoctoral Fellowship (2017), Govt. of India
â€¢ Prize winning poster at the International Conference on Frontiers in Nanoscience and Technology, Cochin Nano 2011
â€¢ ICMR Research Fellowship (2010-2015)
â€¢ Graduate Aptitude Test in Engineering (GATE-2007)
â€¢ 3rd position at University level for MSc-2007
â€¢ 5th position at University level for BSc-2005
â€¢ College topper (1st position) during BSc-2005

Publications/Invited Lectures
â€¢ Narayanan S, Kurian N, Bhat SG. Ultra-small pyomelanin nanogranules abiotically derived from bacteria-secreted homogentisic acid show potential applications in inflammation and cancer. BioNanoScience 2019:10, 191â€“203.

â€¢ Narayanan S, Mony U, Vijaykumar DK, Manzoor K, Bindhu Paul-Prasanth, Menon D. Sequential release of Epigallocatechin gallate and Paclitaxel from PLGA-Casein core/shell nanoparticles sensitizes drug-resistant breast cancer cells. Nanomedicine: Nanotechnology, Biology and Medicine 2015:6:1399-406.

â€¢ Narayanan S, Pavithran M, Viswanath A, Narayanan D, Mohan CC, Manzoor K, Nair SV, Menon D. Sequentially releasing dual-drug-loaded PLGA-casein core/shell nanomedicine: Design, synthesis, biocompatibility and pharmacokinetics. Acta biomaterialia 2014;10:2112-24.

â€¢ Narayanan S, Sathy BN, Mony U, Koyakutty M, Nair SV, Menon D. Biocompatible magnetite/gold nanohybrid contrast agents via green chemistry for MRI and CT bioimaging. ACS applied materials & interfaces 2012;4:251-60.

â€¢ Narayanan S, Prasad T, Nair IC, Jayachandran K. A novel exploitable feature of Chromobacterium violaceum: experimental evidence for Phenol degradation. Novus international journal of biotechnology and bioscience 2012; 1(3)

â€¢ Menon D, Thomas RT, Narayanan S, Maya S, Jayakumar R, Hussain F, Lakshmanan V-K, Nair SV.A novel chitosan/polyoxometalate nano-complex for anti-cancer applications. Carbohydrate Polymers 2011;84:887-893.

â€¢ Narayanan S, Binulal NS, Mony U, Manzoor K, Nair S, Menon D. Folate targeted polymeric 'green' nanotherapy for cancer. Nanotechnology 2010;21:285107.

â€¢ Narayanan S, Prasad T, Jayachandran K. Chromobacterium violaciem- a potential candidate for Biotechnological applications. Advanced Biotech (now The Scitech Journal) 2006;5,06,31-33.

â€¢ Conference Proceeding: Cancer nanomedicine: Leveraging nanotechnology to tackle cancer. Narayanan S. Proceedings of the National Seminar on Emerging trends in Genomic Research, 2019, ISBN: 978-81-935819-4-0.

â€¢ National Science Day Talk, Tackling cancer: A story about taming the â€˜misbehaved, 2020, School of Pharmacy,

Amrita Vishwavidyapeetham.
â€¢ National Seminar on Emerging trends in Genomic Research, Cancer Nanomedicine: leveraging nanotechnology to tackle cancer, 2019, St. Thomas College (Autonomous), Trissur, India
Publication links:

Google Scholar https://scholar.google.co.in/citations?user=3H8Y1m8AAAAJ&hl=en
Pubmed https://www.ncbi.nlm.nih.gov/pubmed/?term=sreeja+narayanan

Research Team

Asish Issac

Adheena P B

Aiswarya P

View Faculties

Dr. Sayuj Koyyappurath

Dr. Sreekanth P M

Dr. Rajesh P P

Dr. Bhavya Balan Chandrika

Dr. Sreeja Narayanan

Dr. Sarita G Bhat

Dr. M. Chandrasekaran

Dr. Ajith Vengellur

Dr. Baby Chakrapani P. S.

featured courses

MSC BIOTECHNOLOGY

4 Semester | Full time | Qualification: CAT

M.Sc Biotechnology course is designed to cover the comprehensive theoretical and practical knowledge to equip graduates with the necessary proficiency to become the next generation of bioscientists to lead new innovations in academia, industry and healthcare. This Masters course includes subjects such as cellular and molecular biology, rDNA technology, genetic engineering, immunology, bioprocess technology, enzymology and bioinformatics. In addition there are elective subjects which the students can choose based on their interests such as environmental biotechnology, animal biotechnology, nano biotechnology, medical and industrial Biotechnology. Students usually do their Masters project work (Semester 4) either in CUSAT or in other prestigious institutes such as IIT, IISc, NIIST and IISER. Career opportunities available for Biotechnology post-graduates includes positions in research institutes, biotechnology companies, pharmaceutical & nutraceutical sectors, pharmacovigilance, fermentation industries, food and dairy industries and bioenergy sector. The department has a team of highly efficient and well qualified teaching faculty with a good experience in teaching and research. There is a breadth of research expertise among the faculty members, with each of them specializing in different thrust areas.
Eligibility: B.Sc Life science Subjects/ Biotechnology from recognised University/Institution.

Syllabus

Mentor-Mentee

PO-PSO

MSC MICROBIOLOGY

4 Semester | Full time | Qualification: CAT

Microbiology, a classical discipline in Biological Sciences, is an extremely diverse field. The Masters course includes basic and application level subjects such as cell and molecular biology, microbial biotechnology, genetic engineering, immunology, bioprocess technology, rDNA technology and marine microbiology. Students usually do their Masters project work (Semester 4) either in CUSAT or in other prestigious institutes such as IIT, IISc, NIIST and IISER. Ample career opportunities are available for Microbiology post-graduates in diverse areas including research institutes, pharmaceutical & nutraceutical sectors, hospitals, analytical laboratories, fermentation industries, food and dairy industries, catering industries, bioenergy sector and in biotechnology companies/start-ups. The department has a team of highly efficient and well qualified teaching faculty with a good experience in teaching and research. There is a breadth of research expertise among the faculty members, with each of them specializing in different thrust areas.
Eligibility: B.Sc Life science Subjects/ Microbiology from recognised University/Institution.

Syllabus

Mentor-Mentee

PO-PSO

PhD in Biotechnology

Full time | Qualification: DAT

PhD degree provides the research fellow advanced and specialized training in a particular area of research. The research areas a PhD student can focus include microbiology, cell & molecular Biology, neurobiology and cancer biology. The choice of research area will depend on the project/faculty that he/she joins. The student has to complete course works (in relevant subjects) during their PhD tenure. Students get an opportunity to participate in national/international conferences and internships during the tenure of PhD program.
Eligibility: Post graduation in Life Science Subjects from a recognised college/ university or M. Phil. Degree in the relevant discipline.

Syllabus

Integrated M.Sc in Biological Sciences

10 Semester | Full time | Qualification: CAT

The Department of Biotechnology offers a five-year Integrated MSc in Biological Sciences. Eligible candidates must have a minimum of 50% in their qualifying examination, with Biology, Physics, and Chemistry as subjects.This interdisciplinary program is designed to immerse students in a research-intensive environment, combining rigorous theoretical coursework with extensive hands-on laboratory training in fields like Genomics, Proteomics, and Molecular Biology. Beyond the classroom, the curriculum emphasizes industry readiness through mandatory internships and a terminal research project, facilitating a direct transition into global PhD programs or high-level roles in the biotech industry.

Syllabus

Mentor-Mentee

PO-PSO

Internship and Dissertation

Both internships and dissertations offer incredible opportunities to deepen your academic knowledge, develop practical skills, and explore potential career paths. If you're interested in undertaking an internship or dissertation, please reach out to a faculty member whose expertise matches your area of interest.