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Golden Jubilee International Online Conference BIOTECHSPECTRUM 2022: 4th to 9th February, 2022 organized by Department of Biotechnology, CUSAT Golden Jubilee International Online Conference BIOTECHSPECTRUM 2022: 4th to 9th February, 2022 organized by Department of Biotechnology, CUSAT Golden Jubilee International Online Conference BIOTECHSPECTRUM 2022: 4th to 9th February, 2022 organized by Department of Biotechnology, CUSAT Golden Jubilee International Online Conference BIOTECHSPECTRUM 2022: 4th to 9th February, 2022 organized by Department of Biotechnology, CUSAT
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Projects
our projects
Dr. Baby Chakrapani P.S.
1. KSCSTE YIPB project - Title: The role of gp130 - associated cytokines in the regulation of adult Neurogenesis - (PI)Duration- 3 years (2017-2020); Sanctioned Amount- 25.3 Lakhs

2. University-Start-up Grant - Title: Generation and characterization of dopaminergic neurons from peripheral blood-derived mononuclear cells (PI) Duration- 3 years (2017-2020); Sanctioned Amount- 2.5 Lakhs

3. UGC-Start-up Grant - Title: Investigating the Role of Hypoxia-Inducible Factor-alpha in Neuronal Homeostasis under Normoxia using Primary Cortical Neuronal Culture (Co-PI) Duration- 3 years (2017-2020); Sanctioned Amount- 10 Lakhs

4. ICMR Extra Mural grant -Exploring the human gut microbiome and metabolome in health and Parkinson’s disease-a window to the gut microbiota brain axis alterations in Parkinson’s disease Multicentre project in collaboration with Sree Chitra Institute of Medical Science (PI) Duration- 3 years (2019- 2022); Sanctioned Amount- 1.2 Crore

5. CUSATECH Foundation and AKAY Natural Ingredients Pvt. Ltd. (University-Industry collaborative project) Development of bioavailable formulations of phytonutrients with cognitive and memory-enhancing properties for the management of neurovegetative conditions and traumatic brain injury. (PI) Duration- 3 years (2020-2023); Sanctioned Amount- 50 Lakhs

6. Chancellors Award grant – Title: Biocompatible 3D Scaffolding through Femtosecond Laser Photopolymerization for Tissue Engineering and Regenerative Medicine (Co-PI) Duration- 3 years (2020-2023); Sanctioned Amount- 4 Crore
Dr. Bhavya Balan Chandrika
1. Designing and Development of GBA1-L444P corrected cells using CRISPR/Cas9 tool as a potential therapy for Gaucher Disease, Funded by DHR/ICMR -2020-23 Grand money- 30lakh

2. Search for the potential biofluid markers for the early diagnosis and effective
prognosis of pulmonary fibrosis, SEED GRANT funded by CUSAT, 2020-2022 Grant Money-2.5lakh
Dr. Sarita G Bhat
1. UGC-SR grants- Whole-genome analysis of marine microbial community for novel feed enzymes
F. No. 41-527/2012/(SR) dated 17-July, 2012; UGC, Dr.Sarita G Bhat- PI 2012-Dec 2015; Sanctioned Amount- Rs. 14,40,800

2. CMLRE-MoES project- Screening and Isolation of Potential bioactive molecules from the Deep sea organisms including bacteria; No.MoES/10-MLR/2/2012 dt 13.02-2008 ;MoES- Dr.Sarita G Bhat- PI ,Dr. M. Chandrasekaran- Co-PI., 2012-2016; Sanctioned Amount- Rs. 87,50,000

3. KSCSTE (Govt. of Kerala) SRS-Salmonella lytic bacteriophages for application as biocontrol agents; F.No.009/SRSHS/2012/ CSTE dated 20th Nov 2013; Dr. Sarita G Bhat- PI; 2014-2017; Sanctioned Amount- Rs. 17,40,600

4. Kerala State Biodiversity Board project- Riverine biodiversity monitoring with reference to mangroves in comparison with pre-flood data; Dr. Sarita G Bhat –PI; Dr.Sreekanth P.M-CoPI;20-12.2018 to 30.6.2019(6.5 months); Sanctioned Amount- Rs. 2,40,000/-

5. Kerala State Biodiversity Board project- Metagenomic analysis of soil microbial diversity in post-flood mangroves; Dr. Sarita G Bhat –PI, Dr. Bindiya E.S –Co-PI,20-12.2018 to 30.6.2019 (6.5 months); Sanctioned Amount- Rs. 6,95,000/-

6. DBT- BIOCARE project- Development of Antibacterial Catheters for Preventing Nosocomial Infections from Therapeutically Modulated Natural Rubber Latex Formulation; Dr. Sailaja G. S-PI, Dr. Sarita G Bhat CoPI, Dr. Ajith Vengellur, 2016-2019; Sanctioned Amount- Rs. 54,00,000/-

7. DST SERB project-Characterization of gonadotropin-releasing hormone and kispeptin systems in the catfish: Heteropneustess fossilis: crosstalks and interactions in the control of gonadotropin secretion; DST, Dr. K.P Joy PI, Dr. Sarita G Bhat Co-PI;2017-2020; Sanctioned Amount- Rs. 49,85,000/-

8 DBT- project Search for novel anticancer Secondary metabolite from endophytic fungi of selected marine algae and evaluation of their mechanism of action; DBT; Dr. Jayabhaskaran PI(IISc), Dr. Sarita G. Bhat PI(CUSAT) ; 41,784,00/- (IISc)+30,732,00/- (DBT, CUSAT);2017-2021

9. UGC-FRPS Mid-career award project- Probiotic modulation of immune response, gut diversity and gut-brain axis in inflammatory/stress models of Danio rerio (zebrafish); Dr. Sarita G Bhat PI; (on UGC website, Sanction not received) Rs. 10,0000/-;2021-24
Dr. Sreekanth P.M.
1. Riverine biodiversity monitoring with reference to Mangroves in comparison with pre-flood data” Kerala State Biodiversity Board (KSBB) Govt. of Kerala (Co-Principal Investigator) 2018-2019

2. “Fine-scale genetic structuring of Mangrove tree Avicennia marina in ecologically important areas of Kerala coast” Research Grant project funded by Startup Research Grant project funded by SERB-DST Govt. of India (Principal Investigator) (2015-2018)

3. Whole-Genome Resequencing of native true mangrove tree- Avicennia marina in eco-geographic regions of Kerala coast: Implication in conservation' Principal Investigator Dr. Sreekanth (ONGOING) (SEED GRANT State Plan Grant of University)
Dr. Anusha Asokan
1. Alginate based engineered materials as adjuvants for therapeutic cancer vaccines period: May 2016- May 2022
Dr. Sneha Yogindran
1. Project title- Exploring the molecular regulation of antiviral silencing during CMD in Cassava, Duration- 2020-2022; Grant money- 2,00,000/-
Dr. Mohanan Valiyaveetil
1. DBT Ramalingaswami grant: Role of Glutamate receptors and associated signaling pathways in Epstein- Barr virus (EBV/HHV-4) mediated oncogenesis

2. DST SERB grant: Repressor element-1 silencing transcription factor (REST) in Epstein- Barr virus biology and pathogenesis
Dr. Sreeja Narayanan
1. Title: Target-specific stealth delivery of clusters of inherently immunostimulatory nanogranules incorporating an immunomodulator with chemotherapeutics for improved breast cancer therapy; Agency: DBT/Wellcome Trust India Alliance (ongoing) 2020-2025; Grant sum: Rs. 1.34 Crores
Postdoctoral projects
The Department hosts Post-Doctoral researchers under various schemes such as UGC-DS Kothari, SERB-National PDF, DST-SERB Startup Grant, DBT Research Associateship, ICMR Research Associateship, Kerala State Post Doctoral Fellowship, and Women Scientist Scheme

1. Development of novel phage nanoparticle hybrid therapy (PNPHT) for nosocomial multidrug-resistant biofilm eradication from animate and inanimate surfaces - Dr. E. Suja, ICMR (2021-2024)
2. Fabrication of Electrospun Collagen and Bacteriophage incorporated polymer scaffolds for wound healing applications - Dr. Jiya Jose, ICMR (2020-2023)
3. Bacterial diversity of water and soil under the influence of Kochi Refinery and its divisions: A metagenomic approach: Dr. Tripti Raghavendra, DBT (2020-2022)
4. Exploring the human gut microbiome and metabolome in health and Parkinson’s disease – a window to the gut microbiota-brain axis alterations in Parkinson’s disease: Dr. Dania Jose, ICMR (2019-2022)
5. Development of bioavailable formulations of phytonutrients with cognitive and memory-enhancing properties for the management of neurovegetative conditions and traumatic brain injury- Dr. Mohind Mohan (RUSA-CUSATech)
Courses Offered